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CasNo： 1125812-58-9
MF： C9H3ClF6O
The invention relates to the field of sy...
The invention discloses a method for syn...
The invention relates to the field of or...
PROBLEM TO BE SOLVED: To provide a compo...
C9H4ClF6NO
1-(3-chloro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroethan-1-one
| Conditions | Yield |
|---|---|
|
C9H4ClF6NO;
With
sulfuric acid;
at -10 - 0 ℃;
for 1.5h;
With
sodium nitrite;
In
water;
at 0 - 20 ℃;
for 2h;
With
phosphinic acid; copper(II) oxide;
In
water;
for 2h;
Reagent/catalyst;
|
87.2% |
ethyl trifluoroacetate,
1-bromo-3-chloro-5-(trifluoromethyl)benzene
1-(3-chloro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroethan-1-one
| Conditions | Yield |
|---|---|
|
1-bromo-3-chloro-5-(trifluoromethyl)benzene;
With
magnesium;
In
diethyl ether;
at 0 ℃;
for 0.5h;
Inert atmosphere;
ethyl trifluoroacetate,;
In
diethyl ether;
at -80 ℃;
for 0.5h;
Inert atmosphere;
With
hydrogenchloride;
In
diethyl ether; water;
at -10 ℃;
|
78% |
trifluoroacetic acid-methyl ester
1-chloro-3-iodo-5-(trifluoromethyl)benzene
ethyl trifluoroacetate,
1-bromo-3-chloro-5-(trifluoromethyl)benzene
4-[3-[3-chloro-5-(trifluoromethyl)phenyl]-4,4,4-trifluoro-1-oxo-2-buten-1-yl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-1-naphthalenecarboxamide
1-[3-chloro-5-(trifluoromethyl)phenyl]-2,2,2-trifluoroethanamine
(2E)-3-[4-(cyclopropylcarbamoyl)-3-trifluoromethylphenyl]acrylic acid
4-[5-[3-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-1-naphthalenecarboxamide
