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  • Product NameNomegestrol
  • CasNo. 58691-88-6
  • MFC21H28O3
  • MW328.452
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Product Details

CasNo： 58691-88-6

MF： C21H28O3

Factory Export Top Purity Nomegestrol 58691-88-6 In Stock

  • Molecular Formula:C21H28O3
  • Molecular Weight:328.452
  • Vapor Pressure:3.32E-12mmHg at 25°C 
  • Melting Point:204-205 °C 
  • Refractive Index:1.573 
  • Boiling Point:502.6 °C at 760 mmHg 
  • PKA:12.99±0.60(Predicted) 
  • Flash Point:271.8 °C 
  • PSA：54.37000 
  • Density:1.17g/cm3 
  • LogP:3.61440 

Nomegestrol(Cas 58691-88-6) Usage

Brand name

LUTENYL

General Description

Nomegestrol acetate, 17-hydroxy-6-methyl-19-norpregna-4,6-diene-3,20-dione acetate,is being investigated as the progestin component of anew oral contraceptive, in combination with the estrogenestradiol. This new combination, NOMAC/E2, is in phaseIII trials and would be the first oral contraceptive to utilizeestradiol itself as the estrogenic component. Structurally,NOMAC is considered a nor-progesterone derivative thatlacks the C19 methyl group in megestrol acetate.

InChI:InChI=1/C21H28O3/c1-12-10-18-16(15-5-4-14(23)11-17(12)15)6-8-20(3)19(18)7-9-21(20,24)13(2)22/h10-11,15-16,18-19,24H,4-9H2,1-3H3/t15-,16-,18-,19+,20+,21+/m1/s1

58691-88-6 Process route

(10R,13S,17R)-17-Acetyl-17-hydroxy-6,13-dimethyl-1,2,8,9,10,11,12,13,14,15,16,17-dodecahydro-cyclopenta[a]phenanthren-3-one
5514-85-2,58691-88-6

(10R,13S,17R)-17-Acetyl-17-hydroxy-6,13-dimethyl-1,2,8,9,10,11,12,13,14,15,16,17-dodecahydro-cyclopenta[a]phenanthren-3-one

Conditions
Conditions Yield
Pregnadien-4,6 (Formel 7a), Kaliummethylat;

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