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CasNo： 22071-15-4
MF： C16H14O3
Appearance： white crystalline solid
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Ketoprofen is white crystalline solid, while it's Molecular Formula is C16H14O3. Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.
The CAS number of Ketoprofen is 22071-15-4.
More information of Ketoprofen 22071-15-4 are:
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Synonyms |
3-Benzoyl-alpha-methylbenzeneacetic acid;Epatec;Oruvail;Orudis;Ketoprofen (JP14/USP);2-(3-Benzoylphenyl)propionic acid;3-Benzoylhydratropic acid;Profenid;Benzeneacetic acid,3-benzoyl-R-methyl-;LAcide (benzoyl-3-phenyl)-2-propionique;Alrheumate;m-Benzoylhydratropic acid;ISO-K;Orudis (TN); |
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CAS Number |
22071-15-4 |
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Molecular Formula |
C16H14O3 |
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Molecular Weight |
254.285 |
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Density |
1.198 g/cm3 |
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Melting Point |
69-71 °C |
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Boiling Point |
431.3 °C at 760 mmHg |
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Flash Point |
147 °C |
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HS CODE |
29183000 |
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PSA |
54.37000 |
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LogP |
3.10570 |
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Pka |
pKa 5.94(MeOH/H2O) (Uncertain) |
Ketoprofen (3-benzoyl-α-methylphenylacetic acid) is a 2-arylpropionic acid potent non-steroidal anti-inflammatory drug. It was first synthesized by French chemist Rhone Poulenc in 1967. In 1973, it was introduced into France and the United States as an anti-inflammatory drug. It has good effects on rheumatism, rheumatoid arthritis, myelitis and gout, and its anti-inflammatory effect is stronger than that of ibuprofen. Ibuprofen. At the same dose, its anti-inflammatory and analgesic effect is 150 times that of aspirin, its antipyretic effect is 4 times that of indomethacin and 100 times that of aspirin. Because ketoprofen has high efficacy, short half-life, It has the advantages of simple metabolism and few and mild adverse reactions, and has been widely used in the treatment of various types of pain, inflammatory symptoms, colds and post-operative anti-inflammatory analgesia.
InChI:InChI=1/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19)/t11-/m0/s1
Articles related to Ketoprofen:
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Article |
Source |
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Ester Prodrugs of Ketoprofen: Synthesis, Hydrolysis Kinetics and Pharmacological Evaluation |
Dhokchawle,Tauro,Bhandari , p. 46 - 50 (2015) |
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Ketoprofen intermediate as well as preparation method and application thereof |
- , (2020/03/12) |
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