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CasNo: 148031-34-9
MF: C35H49N11O9S2
Appearance: White powder
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Acute Coronary Syndrome (ACS) INTEGRILIN? is indicated to decrease the rate of a combined endpoint of death or new myocardial infarction (MI) in patients with ACS (unstable angina [UA]/non-ST-elevation myocardial infarction [NSTEMI]), including patients who are to be managed medically and those undergoing percutaneous coronary intervention (PCI). Percutaneous Coronary Intervention (PCI) INTEGRILIN is indicated to decrease the rate of a combined endpoint of death, new MI, or need for urgent intervention in patients undergoing PCI, including those undergoing intracoronary stenting.
The acetate salt form of eptifibatide (E592000), an arginine-glycine-aspartate-mimetic which reversibly binds to platelets to reduce the risk of cardiac ischemic events.
The CAS number of Eptifibatide is 148031-34-9.
More information of Eptifibatide 148031-34-9 are:
CAS Number |
148031-34-9 |
Density |
1.605 g/cm3 |
Melting Point |
92-98°C |
Refractive Index |
1.742 |
PSA |
374.49000 |
LogP |
1.62840 |
Synonyms for Eptifibatide 148031-34-9:Integrelin;UNII-NA8320J834;N(sup 6)-Amidino-N(sup 2)-(3-mercaptopropionyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide, cyclic(1-6)-disulfide;
The chemical formula of Eptifibatide is C35H49N11O9S2 which containing 35 Carbon atoms,49 Hydrogen atoms,11 Nitrogen atoms,9 Oxygen atoms and 2 Sulfur atoms,and the molecular weight of Eptifibatide is 831.96.
Eptifibatide, also known as E592000, is a cyclic heptapeptide containing 6 amino acids and 1 mercaptopropionyl (des-amino cysteinyl) residue. It is an arginine-glycine-aspartate (RGD) mimetic that reversibly binds to platelets, playing a crucial role in reducing the risk of cardiac ischemic events. Chemically, it is represented as N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-Llysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide, cyclic (1→6)-disulfide. Eptifibatide is produced by solution-phase peptide synthesis, purified by preparative reverse-phase liquid chromatography, and lyophilized.
InChI:InChI=1/C35H49N11O9S2/c36-31(52)26-17-57-56-12-10-27(47)43-22(7-3-4-11-39-35(37)38)32(53)41-16-28(48)44-25(14-29(49)50)34(55)45-24(13-18-15-40-20-6-2-1-5-19(18)20)30(51)21-8-9-23(42-21)33(54)46-26/h1-2,5-6,15,21-26,40,42H,3-4,7-14,16-17H2,(H2,36,52)(H,41,53)(H,43,47)(H,44,48)(H,45,55)(H,46,54)(H,49,50)(H4,37,38,39)/t21?,22-,23-,24-,25-,26-/m0/s1
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