Home > Products > intermediate
CasNo： 459789-99-2
MF： C26H44O4
Quality Factory Supply 99% Pure 6-Ethylchenodeoxycholic acid 459789-99-2 with Efficient Delivery We supply high quality Obeticholic Acid (CAS 459789-99-2), in stock, factory directly supply to clients, lower prices, more competitiveness.
Obeticholic Acid is , while it's Molecular Formula is C26H44O4. 6-Ethylchenodeoxycholic Acid is a derivative of the bile acid Chenodeoxycholic Acid (C291900). 6-Ethylchenodeoxycholic Acid is a potent activator of the farnesoid X nuclear receptor which reduces liver fat and fibrosis in animal models of fatty liver disease.
The CAS number of Obeticholic Acid is 459789-99-2.
More information of Obeticholic Acid 459789-99-2 are:
|
Synonyms |
6α-ethyl-chenodeoxycholic acid;6-Ethyl-CDCA; |
|
CAS Number |
459789-99-2 |
|
Molecular Formula |
C26H44O4 |
|
Molecular Weight |
420.63 |
|
Density |
1.091 g/cm3 |
|
Melting Point |
108-110 °C |
|
Boiling Point |
562.9 °C at 760 mmHg |
|
Flash Point |
308.3 °C |
|
HS CODE |
2918199890 |
|
PSA |
77.76000 |
|
LogP |
5.11400 |
|
Pka |
4.76±0.10(Predicted) |
Obeticholic acid is a potent and selective farnesoid X receptor agonist that promotes the flow of bile in the liver. The drug was approved by the USFDA for the treatment of the rare chronic liver disease primary biliary cholangitis (PBC) in combination with ursodeoxycholic acid (UDCA) in adults with inadequate response to UDCA or as a single agent therapy in adults unable to tolerate UDCA. Obeticholic acid was discovered at the Università de Perugia and developed by Intercept Pharmaceuticals. Obeticholic acid has also been granted orphan drug designation for the treatment of primary sclerosing cholangitis and primary biliary cirrhosis and has received breakthrough therapy designation for the treatment of patients with nonalcohol steatohepatitis (NASH) with liver fibrosis.
InChI:InChI=1/C26H44O4/c1-5-17-21-14-16(27)10-12-26(21,4)20-11-13-25(3)18(15(2)6-9-22(28)29)7-8-19(25)23(20)24(17)30/h15-21,23-24,27,30H,5-14H2,1-4H3,(H,28,29)/t15-,16-,17-,18-,19+,20+,21+,23+,24-,25-,26-/m1/s1
Articles related to Obeticholic Acid:
Qingdao Chengyuan Kaisheng Industry and Trade Co., Ltd. is a quality supplier and manufacturer of Obeticholic Acid . You can buy high quality, low price Obeticholic Acid 459789-99-2 here. Contact us.
