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CasNo： 50-55-5
MF： C33H40N2O9
Appearance： off-white crystalline powder
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Reserpine is off-white crystalline powder, while it's Molecular Formula is C33H40N2O9. An inhibitor of transport of biogenic amines into adrenal chromaffin granules
The CAS number of Reserpine is 50-55-5.
More information of Reserpine 50-55-5 are:
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Synonyms |
3b,20a-Yohimban-16b-carboxylic acid, 18b-hydroxy-11,17a-dimethoxy- methyl ester 3,4,5-trimethoxybenzoate (ester)(8CI);11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acidmethyl ester;3,4,5-Trimethoxybenzoyl methyl reserpate;Hiposerpil;Loweserp;Methylreserpate 3,4,5-trimethoxybenzoate (ester);Reserpic acid methyl ester 3,4,5-trimethoxybenzoate (ester); |
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CAS Number |
50-55-5 |
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Molecular Formula |
C33H40N2O9 |
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Molecular Weight |
608.689 |
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Density |
1.329 g/cm3 |
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Melting Point |
~265 °C (dec.) |
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Boiling Point |
700.058 °C at 760 mmHg |
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Flash Point |
377.182 °C |
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HS CODE |
29399990 |
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PSA |
117.78000 |
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LogP |
4.10900 |
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Pka |
6.6(at 25℃) |
Reserpine is an alkaloid isolated from dried roots of R. serpentine, which is used in traditional Indian medicine. Reserpine irreversibly inhibits both human isoforms of vesicular monoamine transporter, VMAT1 and VMAT2 (Kis = 34 and 12 nM, respectively). As this leads to metabolism of monoamines, reserpine is used to experimentally deplete monoamines in animals. Reserpine also inhibits the multidrug resistance protein P-glycoprotein (IC50 = 0.5 μM).
InChI:InChI=1/C33H40N2O9/c1-38-19-7-8-20-21-9-10-35-16-18-13-27(44-32(36)17-11-25(39-2)30(41-4)26(12-17)40-3)31(42-5)28(33(37)43-6)22(18)15-24(35)29(21)34-23(20)14-19/h7-8,11-12,14,18,22,24,27-28,31,34H,9-10,13,15-16H2,1-6H3/p+1/t18-,22+,24-,27+,28+,31+/m1/s1
Articles related to Reserpine:
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Article |
Source |
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The acid catalysed C3 epimerization of reserpine and deserpidine. |
Gaskell,Joule , p. 4053 - 4063 (1967) |
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Muccino,Serico , p. 529,532 (1978) |
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