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CasNo: 56-47-3
MF: C23H32O4
Appearance: Off-white solid
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Deoxycorticosterone acetate is Off-white solid, while it's Molecular Formula is C23H32O4. Deoxycorticosterone acetate has been used to induce hypertensive pregnancy. It has also been used to investigate the effect of low epicatechin dosing on the cardiovascular function of deoxycorticosterone acetate (DOCA)-salt hypertensive rats.
The CAS number of Deoxycorticosterone acetate is 56-47-3.
More information of Deoxycorticosterone acetate 56-47-3 are:
Synonyms |
11-Deoxycorticosterone,acetate (8CI);Pregn-4-ene-3,20-dione, 21-hydroxy-, acetate (7CI);11-Deoxycorticosterone 21-acetate;11-Desoxycorticosterone acetate;21-Acetoxy-3,20-diketopregn-4-ene;21-Acetoxypregn-4-en-3,20-dione;21-Acetoxypregn-4-ene-3,20-dione;21-Hydroxypregn-4-ene-3,20-dione 21-acetate;21-Hydroxypregn-4-ene-3,20-dione acetate;21-Hydroxyprogesterone 21-acetate;4-Pregnene-3,20-dione 21-acetate;4-Pregnene-3,20-dione-21-ol acetate;Arcort;Bio-Corten;Cortacet;Cortate;Cortenil;Cortesan;Cortexone acetate;Cortifar;Cortigen;Cortinaq;Cortiron;Cortivis;Cortixyl;DCA;DOC acetate;DOCA;Decorten;Decortin;Decosteron;Decosterone;Decostrate;Deoxycorticosterone21-acetate;Deoxycorticosterone acetate;Deoxycortone acetate;Descorterone;Descotone;Desoxycorticosterone acetate;Desoxycortone acetate;Dorcostrin;Doxo;Doxycamon;Krinocorts;NSC 9567;Ocriten;Ocritena;Percorten;Percotol;Primocort;Primocortan;Sincortex;Steraq;Syncort;Syncorta;Syncortyl;Unidocan; |
CAS Number |
56-47-3 |
Molecular Formula |
C23H32O4 |
Molecular Weight |
372.505 |
Density |
1.14 g/cm3 |
Melting Point |
157 °C |
Boiling Point |
504.1 °C at 760 mmHg |
Flash Point |
218 °C |
HS CODE |
2937290000 |
PSA |
60.44000 |
LogP |
4.26670 |
Deoxycorticosterone acetate (DOCA) is an endogenous neurosteroid derived from progesterone, which is found in the brain and peripheral circulation. It serves as both a mineralocorticoid and a glucocorticoid, playing a crucial role in the regulation of various physiological processes. DOCA is used to treat adrenocortical insufficiency or Addison's disease and has been shown to improve insulin sensitivity. It also acts as a precursor to glucocorticoid corticosterone and the GABAergic neuroactive steroid (3α,5α)-3,21-dihydroxypregnan-20-one. DOCA is an off-white solid and is available under the brand names Doca (Organon) and Percorten (Novartis). It was previously known as Deoxycortone.
InChI:InChI=1/C23H32O4/c1-14(24)27-13-21(26)20-7-6-18-17-5-4-15-12-16(25)8-10-22(15,2)19(17)9-11-23(18,20)3/h12,17-20H,4-11,13H2,1-3H3/t17?,18?,19?,20-,22+,23+/m1/s1
Articles related to Deoxycorticosterone acetate:
Article |
Source |
- |
Rakhit,Gut , p. 1196 (1968) |
Regioselective esterification of polyhydroxylated steroids by Candida antarctica lipase B |
Bertinotti, Anna,Carrea, Giacomo,Ottolina, Gianluca,Riva, Sergio , p. 13165 - 13172 (2007/10/02) |
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