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CasNo： 16773-42-5
MF： C7H10ClN3O3
Appearance： Crystalline solid
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Ornidazole is Crystalline solid, while it's Molecular Formula is C7H10ClN3O3. estrogen
The CAS number of Ornidazole is 16773-42-5.
More information of Ornidazole 16773-42-5 are:
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Synonyms |
Tiberal;1-Chloro-3-(5-(hydroxy(oxido)amino)-2-methyl-1H-imidazol-1-yl)-2-propanol;Ornidazol [INN-Spanish];alpha-(Chloromethyl)-2-methyl-5-nitro-1H-imidazole-1-ethanol (9CI);Madelen;Imidazole-1-ethanol, .alpha.- (chloromethyl)-2-methyl-5-nitro-;Prestwick_584;Ornidazolum [INN-Latin];1H-Imidazole-1-ethanol, .alpha.-(chloromethyl)-2-methyl-5-nitro-;Ormidazole;S-(-)-ornidazole; |
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CAS Number |
16773-42-5 |
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Molecular Formula |
C7H10ClN3O3 |
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Molecular Weight |
219.628 |
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Density |
1.53 g/cm3 |
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Melting Point |
85-90 ºC |
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Boiling Point |
443.2 ºC at 760 mmHg |
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Flash Point |
221.9 ºC |
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HS CODE |
2933290090 |
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PSA |
83.87000 |
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LogP |
1.22260 |
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Pka |
2.4 ± 0.1(at 25℃) |
Ornidazole is an orally bioavailable 5-nitroimidazole derivative with antibacterial and antiprotozoal activities. Ornidazole inhibits the growth of clinical isolates of B. fragilis (MICs = 0.5-5 μM) and various anaerobic bacteria when used at concentrations ranging from less than 0.1 to 3.2 μg/ml. It also inhibits the growth of Giardia isolates (IC50s = 0.01-0.47 μg/ml). Oral administration of ornidazole reduces T. vaginalis and T. foetus infection in mice and E. histolytica infection in rats with curative dose (CD50) values of 37, 3, and 10 mg/kg, respectively. Ornidazole (400 mg/kg per day) induces infertility in male rats within 7 days and inhibits spermatozoa binding to rat oocyte zona pellucida.
InChI:InChI=1/C7H10ClN3O3/c1-5-9-3-7(11(13)14)10(5)4-6(12)2-8/h3,6,12H,2,4H2,1H3
Articles related to Ornidazole:
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Article |
Source |
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Nitroimidazole derivative, preparation method and application thereof |
- Paragraph 0013; 0039-0041, (2021/05/12) |
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Synthesis method of 5-nitroimidazole drugs |
- Paragraph 0039; 0040; 0043-0050, (2020/04/06) |
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