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CasNo: 68786-66-3
MF: C14H9Cl3N2OS
Appearance: off-white solid
InChI:InChI=1/C14H9Cl3N2OS/c1-21-14-18-9-5-8(16)12(6-10(9)19-14)20-11-4-2-3-7(15)13(11)17/h2-6H,1H3,(H,18,19)
The invention provides a preparation met...
The invention discloses a synthesis meth...
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5-chloro-6-(2,3-dichlorophenoxy)-2,3-dihydro-1H-1,3-benzodiazole-2-thione
methyl iodide
triclabendazole
Conditions | Yield |
---|---|
With
potassium hydroxide;
In
ethanol; water;
at 10 - 50 ℃;
for 20h;
|
94% |
6-chloro-5-(2,3-dichlorophenoxy)-1H-benzimidazole-2-thiol
dimethyl sulfate
triclabendazole
Conditions | Yield |
---|---|
6-chloro-5-(2,3-dichlorophenoxy)-1H-benzimidazole-2-thiol; dimethyl sulfate;
In
methanol; water;
at 60 ℃;
for 0.5h;
With
sodium carbonate;
In
water;
at 60 ℃;
for 1.5h;
|
81.7% |
5-chloro-6-(2,3-dichlorophenoxy)-2,3-dihydro-1H-1,3-benzodiazole-2-thione
methyl iodide
4-chloro-5-(2,3-dichlorophenoxy)-1,2-phenylenediamine
6-chloro-5-(2,3-dichlorophenoxy)-1H-benzimidazole-2-thiol
Triclabendazole sulfoxide
6-chloro-5-(2,3-dichlorophenoxy)-1-methyl-2-methylthio-1H-benzimidazole